David A. Cory, RPh, MBA
President and Chief Executive Officer, Business Founder
David Cory is an industry veteran with over 25-years of experience in large pharmaceuticals, emerging stage biotechnology, and specialty pharmaceutical organizations with an established track record of operational performance, including 5 successful Orphan Designation drug programs.
Cory is President and CEO, Director, and business founder of Eiger BioPharmaceuticals, leading the company since its founding in 2008 and responsible for negotiating the company’s multiple technology and product licenses from Stanford University, Merck, Nippon Kayaku, Janssen, BMS and The Progeria Research Foundation. Prior to Eiger, Cory was President and Chief Operating Officer of Prestwick Pharmaceuticals, an orphan CNS specialty pharmaceutical company, which was acquired by Biovail for $160 million in 2007. Previously, Cory was a Co-Founder at CoTherix, an orphan pulmonary arterial hypertension company, which was acquired by Actelion for $425 million in 2006. Cory began his biotech career at InterMune, focused on developing orphan products for idiopathic pulmonary fibrosis, where he was a Senior Vice President and a key executive in the company IPO, building and managing the company’s commercial organization, in-licensing 4 products and raising over $400 million in the capital markets. InterMune was ultimately acquired by Roche for $8 billion in 2013. Cory spent over a decade in large pharma in positions of increasing responsibilities in commercial operations at Glaxo, Glaxo Wellcome, and Glaxo Smith Kline where he led teams in oncology, critical care, CNS, infectious disease and respiratory therapeutic areas, and directed 10 newly approved pharmaceutical product launches. Cory began his pharmaceutical career in sales at The Upjohn Company.
Cory earned a Bachelor of Science in Pharmacy from the University of Cincinnati, College of Pharmacy, was board certified in Pharmacy in the state of Ohio, and holds a Master’s Degree in Business Administration from the University of Maryland.
Sri Ryali, MBA
Chief Financial Officer
Mr. Ryali brings over fifteen years of finance and commercial experience to Eiger. He was most recently at Aimmune Therapeutics, Inc., where he was Vice President of Finance, responsible for building and leading the finance department from Aimmune’s 2015 initial public offering, and subsequently was a key executive involved in operational preparation for product approval. Previously, Mr. Ryali led U.S. Financial Planning and Analysis at Jazz Pharmaceuticals and was Head of Corporate Finance at Onyx Pharmaceuticals, Inc., until the company was acquired by Amgen, Inc. in 2013. Following the acquisition, Mr. Ryali continued as Head of R&D, Technical Operations, and Medical Affairs Finance at Onyx. Mr. Ryali began his career in biopharmaceutical companies at Amgen Inc., where he held positions of increasing responsibility in the finance organization.
Mr. Ryali earned a BA from UCLA with a double major in Economics and Microbiology, Immunology & Molecular Genetics and an MBA from UCLA Anderson School of Management.
David Apelian, MD, PHD, MBA
Chief Operating Officer
Executive Medical Officer
David Apelian brings extensive clinical development and regulatory experience, spanning 17 years between large pharma and biotechnology companies in all phases of development ranging from discovery to registration, across multiple therapeutic areas including gastroenterology, hepatology, immuno-oncology, infectious diseases, and rare diseases.
Dr. Apelian was most recently Executive VP and Chief Medical Officer of Achillion Pharmaceuticals, Inc., a position he held since 2013. At Achillion, he was responsible for creating portfolio strategy and managing the company’s clinical development programs. He was instrumental in securing a partnership between Achillion and J&J, which resulted in a $225 million equity investment. More recently, he led the rare disease development program for novel small-molecule complement factor D inhibitors for alternative pathway-mediated diseases. From 2005 to 2013, Dr. Apelian was Chief Medical Officer and subsequently head of all R&D and Regulatory Affairs for GlobeImmune. He was previously at Bristol-Myers Squibb where he served as Clinical Director and Medical Leader for development of Baraclude® (entecavir) for chronic HBV through NDA filing. Prior to that, Dr. Apelian was Clinical Director in the Department of Hepatology & Gastroenterology at Schering Plough, where he coordinated a supplemental NDA filing for interferon alpha-2b and ribavirin for the treatment of pediatric patients with chronic HCV.
Dr. Apelian completed his residency training in pediatrics at New York Hospital, Cornell Medical Center and is board certified in Pediatrics. He received a PhD in Biochemistry from Rutgers University, an MD from the University of Medicine and Dentistry of New Jersey and an MBA from Quinnipiac University. He earned a BA in Biochemistry from Rutgers University.
Stephana Patton, PhD, JD
General Counsel, Corporate Secretary, and Chief Compliance Officer
Stephana Patton brings 20 years of experience creating portfolio value at publicly-traded biotechnology and pharmaceutical companies. She was formerly the General Counsel, Corporate Secretary, and Chief Compliance Officer of BioTime, Inc., a clinical-stage biotechnology company focused on the development and commercialization of novel therapies for the treatment of degenerative diseases. Prior to BioTime she was the General Counsel and Commercial Compliance Officer at BioDelivery Sciences, a publicly-traded specialty pharmaceutical company. Prior to BioDelivery Sciences, she held various senior management positions, including leading Intellectual Property (IP) and Licensing at Salix Pharmaceuticals, a global pharmaceutical company that was acquired for $11.2 Billion in 2015. Prior to joining Salix, Stephana was in private practice at a large international law firm known for its IP and corporate securities practices. Her practice focused on counseling clients on IP-related matters as well as licensing transactions for biotechnology and pharmaceutical companies at varying stages of product development. Dr. Patton earned a Juris Doctor (J.D.) degree from the Boston University School of Law and a Ph.D. in Biochemistry, Cell and Developmental Biology from Emory University.
James P. Shaffer, MBA
Chief Business Officer
James Shaffer brings extensive commercial leadership and business experience with over 20 years of experience with large pharmaceuticals, emerging biotechnology and specialty pharmaceutical companies in Infectious Disease, Neurology, Oncology, GI and Pulmonary Care.
Prior to joining Eiger, Mr. Shaffer served as Vice President and Chief Commercial Officer for Halozyme Therapeutics from 2011 to 2014 where he was responsible for Sales, Marketing and Business Development overseeing the re-launch of Hylenex® and product development in Diabetes and Oncology. From 2007-2011, Mr. Shaffer was Executive Vice President and Chief Commercial Officer responsible for Sales, Marketing, Business Development and Manufacturing with Clinical Data, Inc., who developed Viibryd®, a novel antidepressant, which was acquired by Forest Laboratories for $1.2 billion. Mr. Shaffer was Vice President of Commercial Operations for New River Pharmaceuticals which developed Vyvanse® for the treatment of ADHD and was acquired by Shire for $2.6 billion in 2007. From 2004-2007, he was Senior Director of Commercial Operations for Prestwick Pharmaceuticals overseeing the collaboration with Cambridge Labs for Xenazine®, an Orphan CNS specialty product, and responsible for the development of the companies commercial capabilities in the US and Canada. From 2001-2004, Mr. Shaffer was the National Sales Director for InterMune. Mr. Shaffer spent the first 10 years of his career in numerous sales and marketing positions of increasing responsibility with Merck and GlaxoSmithKline.
James Shaffer is a graduate of the Ohio State University where he earned a B.S. Degree in Economics and an M.B.A..
Lisa Porter, MD
Chief Medical Officer, Metabolic Diseases
Lisa Porter brings more than 15 years of experience in developing medicines for diabetes and metabolic diseases with a singular focus on bringing innovative therapies to patients with high unmet need. From 2004 to 2013, Dr. Porter served as Vice President, Medical Development for Amylin Pharmaceuticals where she led the R&D efforts for the Amylin-Lilly Alliance culminating in the approval of the GLP-1 agonist Bydureon, the first once weekly treatment for Type 2 diabetes. From 1999-2004, Dr. Porter held progressively increasing leadership positions at GlaxoSmithKline Pharmaceuticals with responsibilities for the clinical strategy for Avandia diabetes treatment and early obesity compounds. Prior to joining GlaxoSmithKline, she served as Associate Medical Director for Zeneca Pharmaceuticals from 1997 to 1999. Dr. Porter earned a BS in Biology from the College of William & Mary, an MD from Duke University and completed fellowship training in Endocrinology and Hypertension at Brigham and Women’s Hospital/Harvard Medical School.
Dr. Colin Hislop, M.B.B.S.
Senior Medical Advisor
Dr. Hislop has over 30 years of experience in drug development including small molecules, peptides and biologics, across therapeutic areas in both large pharma and start-up companies.
Dr. Hislop began his industry career at Eli Lilly as Medical Director of Endocrinology for insulin and growth hormone. He later led the development of Actonel® through initial FDA approvals for osteoporosis at Proctor & Gamble. He was next Vice President of Clinical Development at CV Therapeutics where he worked on the development and NDA for Ranexa® for angina. He then became Vice President and Head of Clinical Development at Peninsula Pharmaceuticals developing doripenem, a beta-lactam antibiotic for systemic infections, through Phase 2, acquired by J&J. He was later Chief Medical Officer at Anthera and Versartis. During his career, Dr. Hislop has been involved in all phases of drug development from IND to Phase 4,and has led numerous US, European and global regulatory filings, including 4 NDAs.
Dr. Hislop earned a Bachelor of Science in Medical Biochemistry from the University of Surrey and a Bachelor of Medicine, Bachelor of Surgery (M.B.B.S.) at the University of London.
Senior Vice President, Clinical Affairs and Progeria Lead
Rich Franco has been in the healthcare industry for over 25 years. He has held leadership roles across a variety of functional areas including commercial, marketing research, regulatory affairs, pharmacovigilance, managed markets, customer service and medical affairs. Mr. Franco joined Eiger in 2016 as the VP of Clinical Strategy. He is responsible for alignment between clinical and commercial functions across all of Eiger’s development programs. He is also leading the company’s efforts to develop and launch a global expanded access program for children with Progeria. Before joining Eiger BioPharmaceuticals he served as the Vice President and General Manager of Valeant Pharmaceutical’s Pain and Hospital divisions. While there he played a significant role in gaining FDA approval and launching Relistor® tablets for opioid induced constipation. In 2014 Mr. Franco joined Sprout Pharmaceuticals as the corporate officer responsible for commercial, medical affairs and pharmacovigilance. He played an essential role in advisory committee preparations and gaining FDA approval for Addyi®, the first drug approved for female hyposexual desire disorder. While at Sprout he led the company’s efforts to develop one of the industry’s most comprehensive Risk Evaluation and Mitigation Strategies (REMS). Earlier in Mr. Franco’s career he co-founded Arbor Pharmaceuticals and held leadership positions at GlaxoSmithKline, Slate Pharmaceuticals, Clinical Data Inc and LipoScience. Mr. Franco has also been a consultant to Halozyme Pharmaceuticals, BASF, Intrexon, IQVIA, Novan Pharmaceuticals, Salix Pharmaceuticals, Dara BioSciences, Talecris and Ashfield Commercial Services.
INGRID CHOONG, PHD
VICE PRESIDENT INVESTOR RELATIONS AND CORPORATE DEVELOPMENT
Ingrid Choong brings over 15 years of experience within the biotechnology/pharmaceutical industry. Dr. Choong joined Eiger as a member of the founding team in 2008 as a Principal Scientist, responsible for lead identification and development of compounds targeting NS4B on the HCV genome. As the company shifted focus to its first orphan program in HDV, Dr. Choong was a key team member involved in agency interactions, clinical activities, investigator and KOL interactions, and scientific conferences. She was also an active member of the team involved in the diligence and licensing process, resulting in the addition of Post Bariatric Hypoglycemia and Lymphedema to our orphan disease pipeline. During the process of Eiger becoming a public company, Dr. Choong was a member of the roadshow team, interacting with investors, research analysts, and investment banks. She has continued to work in this capacity, and has earned the trust and respect of these important audiences. In the second half of 2017, in addition to investor relations and corporate development responsibilities, Ingrid led an internal and external cross-functional team that delivered a HDV briefing package to the FDA, setting the stage for a positive face to face meeting in February. Prior to joining Eiger, she was a senior scientist at Sunesis Pharmaceuticals from 1999 to 2008 identifying small-molecule inhibitors targeting protein-protein interactions.
Dr. Choong earned a BS in Chemistry from the California Institute of Technology and a PhD in Chemistry from the University of California at Berkeley.
John Ferraro, MBA
Vice President, Clinical Operations
John Ferraro brings over 25 years of clinical development experience within the biotechnology/pharmaceutical industry. Prior to joining Eiger, John was the Managing Consultant at JnC Clinical where he was the Acting Vice President of Clinical Operations at several organizations including Medical Device, Global CRO, and Generic areas. Before his consultancy, John was the Vice President of Clinical Operations for Fate Therapeutics, Inc. While at Fate, he rebuilt the clinical and data management departments while being accountable for strategy, planning, and execution of all clinical programs in all phases of development. Prior to Fate, John spent over 10 years at GlobeImmune, Inc. as Senior Director of Clinical Operations. There, John created and implemented the infrastructure of the clinical operations department globally. He was accountable for operational oversight of all clinical development programs within therapeutic areas including oncology and infectious disease in Phases 1 – 3. John spent his early career as a regional CRA for SmithKline Beecham and Pfizer where he performed all site management activities.
He was also a clinical research coordinator at a clinical research asthma and allergy clinical site. He earned his BS in Science and his MBA at University of Phoenix.