Eiger Biopharmaceuticals is a clinical-stage biopharmaceutical company committed to developing and commercializing novel products for the treatment of Orphan diseases.  Eiger has built a diverse, late-stage portfolio of well-characterized product candidates with the potential to address diseases for which the unmet medical need is high, a novel biology for treatment has been identified, and for which an effective therapy is urgently needed.  The Eiger management team has extensive experience in the clinical development and commercialization of a broad range of therapeutics, with special expertise in Orphan Designation drugs.  Eiger is located in Palo Alto, California.

Reports to: Vice President, Clinical Operations

About Eiger Biopharmaceuticals, Inc.

Eiger is a small, rapidly growing biotech company based in Palo Alto, CA.  Eiger is a public company and has 3 compounds in Phase 2 development and 1 compound in Phase 3 development spanning different therapeutic areas. We are a fast paced, lean organization with an emphasis on creating an environment that is conducive to excellent communication, great team work, creativity and exceptionally high quality output.

Position Description:

The Associate Director/Director of Clinical Operations will provide leadership and direction ensuring optimal productivity and optimization of operational resources for new and ongoing clinical trials of compounds in the various therapeutic areas. The candidate will be highly motivated, proactive, have excellent verbal and written communication skills, extensive experience and value a collaborative environment and a team approach. As well as working with internal staff and outside partners to optimize current and future trials, there is an opportunity to create clinical operations infrastructure including SOPs with an emphasis on building cohesive, high performance teams. The candidate will be responsible for ensuring an optimal level of consistency of clinical operations processes across indications and trials while allowing flexibility appropriate to different indications. The current teams are lean, and highly efficient and use outsourced resources. This position will oversee operational activities with an emphasis on excellent clinical trial execution within timelines and budget resulting in high quality data that will support registration.


  • Be a leading member of a highly productive, highly motivated Clinical Operations teams and work to identify and eliminate any barriers to forward progress
  • Assist in the development of Clinical Operations infrastructure including SOPs, work instructions and study tools. Implement these across indications and teams. Contribute to SOP development in other departments.
  • Continuous evaluation of clinical trial operations processes to identify and address strengths and weaknesses and leverage lesson’s learned across the program
  • Mentor staff and provide opportunities for their advancement and promotion from within. Establish and nurture an environment that promotes highly effective teams, a proactive approach and personal growth for team members
  • Work with senior management on strategic initiatives and implement across the teams
  • Provide senior management with timely updates on progress and changes in scope, schedule and resources
  • Work effectively with other internal disciplines to enhance the efficiency of the conduct of clinical trials
  • Assist in the development of clinical study budgets and resource projections
  • Oversee and contribute to CRO and vendor identification and selection process. Participate in CRO governance and problem solve as needed.
  • Work with teams to establish/maintain positive, productive relationships with investigators, thought leaders and service partners (contractors, consultants, CROs and vendors)
  • Oversee/manage the development process for protocols, amendments, investigational brochures, CRFs, CSRs and other study-specific documents coordinating input from the various functional teams
  • Oversee the organization of investigator, expert, and steering committee meetings
  • Regularly assess prioritization of activities across studies and teams. As needed, identify operational resource needs and recruit appropriate candidates with a focus on maintaining the Eiger core values.
  • Lead cross-functional teams
  • Oversee/manage the development process for protocols, amendments, investigational brochures, CRFs, CSRs and other study-specific documents coordinating input from the various functional teams
  • Oversee and contribute to the organization of investigator, expert, data monitoring and steering committee meetings
  • Manage key study parameters (e.g. start-up activities, drug preparation, enrollment, data collection, etc) and proactively identify solutions when issues arise

Education/Experience Requirements:

  • Solid clinical trial management experience. Hands-on experience with all clinical trial components (e.g. monitoring, data management, contracts, report writing, etc.)
  • Minimum 10 years of experience in the pharmaceutical industry with approximately 5-6 years managing clinical trials and 4 – 5 years managing people
  • Comprehensive understanding of pharmaceutical regulatory requirements and impact on clinical trial operations
  • Experience managing complex situations with CROs and other vendors. Be comfortable working at both a detailed level and a big picture level when necessary.
  • Excellent strategic skills with the ability to influence decisions at a senior level, both internally and externally, and to communicate complex clinical issues in a scientifically sound and understandable way.
  • Experience with building clinical operations infrastructure including writing of SOPs, developing and implementing development tools
  • Demonstrated leadership ability with experience leading cross-function teams
  • Excellent interpersonal skills with exceptional project and people management skills
  • Energetic, self-starter, able to multi-task and thrive under pressure and tight timelines
  • BS/RN, PA, NP, PharmD degree or equivalent in a scientific or health care field desirable
  • Must be flexible, detail-oriented with the ability to work as a team player and the ability to work in a fast-paced environment
  • Travel required

Please submit resumes to

Eiger offers an excellent compensation package including competitive compensation and benefits package. Regular full-time employees are eligible for the following benefits:

Insurance Coverage

Medical/Dental/Vision/Prescription Coverage
Eiger’s group health plans includes medical, prescription, dental and vision insurance. The plan offers HMO and PPO options that provides comprehensive medical coverage.

Life Insurance/AD&D and Voluntary Supplemental Life Insurance
Employees are covered by group life insurance through the company and also for accidental death and dismemberment coverage. Employees are also offered the opportunity to purchase voluntary life insurance at competitive rates for themselves and their family members.

Short-Term Disability and Long-term Disability
The Company provides a policy that may replace up to 66.67% of your salary, up to a maximum benefit of $2,308 per week, for qualifying disabilities, for up to a maximum benefit of 180 days.

The Company provides a policy that may replace up to 66.67% of your salary, up to a maximum benefit of $10,000 per month, for qualifying disabilities. A waiting period of 180 days will apply.

Employee Assistance Program (EAP)
The EAP is available at no cost, even if you don’t enroll in Eiger group benefits. You and your family members may access free, confidential counseling and referral services. This program provides 24-hour confidential assistance with personal, family and work-related concerns – plus online resources.

Voluntary Programs

Flexible Spending Account (FSA) & Dependent Care Spending Account
FSAs help you pay for eligible out-of-pocket health care and dependent day care expenses on a pre-tax basis. You determine your projected expenses for the Plan Year and then elect to set aside a portion of each paycheck into your FSA. For the 2012-2013 Plan Year you may contribute from $200 to $5,000 to each FSA

Pre-Tax Commuter Benefits:
The commuter benefit plan allows you to set aside pre-tax dollars to pay for eligible commuting costs, such as expenses for parking, public transit and alternative forms of transportation. Passes can be delivered right to your home, or you can simply submit monthly receipts for reimbursement

Time Off

Paid Holidays
Eiger provides its employees with ten paid holidays and two floating holidays per year.

During the first three years of continuous, full-time employment, Eiger employees accrue five hours of vacation per pay period, up to a maximum of 120 hours per year. After three years of service, employees earn 160 hours per year. The maximum amount of vacation that may be accrued is 160 hours.

*The information contained herein is for informational purposes only and subject to change without notice. This document is just an overview.

To protect the interests of all parties involved, Eiger requires a signed agreement to be in place prior to the presentation of any candidates. Eiger does NOT accept unsolicited resumes from any source other than directly from candidates for either current or future positions. Submission of unsolicited resumes in advance of a signed agreement between Eiger and the recruiter does not create any implied obligation on the part of Eiger.

If you are interested in developing a recruiting relationship with us, please send your company information including references to:

Or mail to:
Human Resources
Eiger BioPharmaceuticals, Inc.
350 Cambridge Ave, Suite 350
Palo Alto, CA  94306

About Eiger

Therapeutic Areas